Clometryl
Overview
Clometryl
Ovules, 500 mg/200 mg/100 mg/15 mg
COMPOSITION
Each ovule contains: metronidazole 500 mg, chloramphenicol 200 mg, natamycin 100 mg, hydrocortisone acetate 15 mg.
Excipients: semi-synthetic solid glycerides.
WHAT IT IS USED FOR
A combination medicine for the local treatment of inflammations of the vagina and cervix (vaginitis and cervicitis) caused by bacteria, fungi or protozoa, including mixed infections involving Trichomonas vaginalis, Candida, Mycoplasma or Chlamydia. It is also used to prevent infections in gynaecological procedures and before a Pap smear.
HOW IT WORKS
The components act together locally: metronidazole targets anaerobic bacteria and protozoa (including Trichomonas vaginalis), chloramphenicol provides broad-spectrum antibacterial action, natamycin acts against fungi (including Candida), and hydrocortisone reduces inflammation, swelling and discomfort.
HOW TO USE
Administer deep into the vagina, one ovule per day, in the evening before bedtime. Treatment course: 7 days. Do not use during menstruation. To prevent reinfection, simultaneous treatment of the sexual partner is recommended. For adults aged 18 years and over only.
WHEN IT SHOULD NOT BE USED
hypersensitivity to metronidazole, chloramphenicol, natamycin, hydrocortisone acetate or to any of the excipients;
bone marrow suppression;
acute intermittent porphyria;
glucose-6-phosphate dehydrogenase deficiency;
severe hepatic and/or renal impairment;
pregnancy and breast-feeding;
children and adolescents under 18 years of age.
Important to know
Use with caution if you have a history of blood disorders, severe or progressive neurological conditions or Cockayne syndrome; regular blood tests and monitoring may be required.
Avoid alcohol during treatment and for 24–48 hours afterwards. The ovules may reduce the effectiveness of latex or rubber condoms and diaphragms — use alternative contraception during treatment and for a further 5 days. Sexual intercourse should be avoided during treatment. Do not drive or operate machinery if you experience dizziness, drowsiness, confusion, seizures or visual disturbances.
Read the package leaflet carefully before use.
Possible side effects
Local: burning, irritation, itching, rash or erosions in the genital area.
Very rare or with unknown frequency: allergic reactions (including anaphylactic shock), blood disorders (leukopenia, neutropenia), headache, dizziness, drowsiness, seizures, psychiatric disturbances, vision or hearing disturbances, metallic taste, nausea, abdominal pain, increased liver enzymes, severe skin reactions, darkening of urine.
If side effects occur, stop using the product and consult a doctor or pharmacist.
STORAGE
Store in the original packaging, protected from light, below 25 °C. Keep out of the reach of children. Shelf life: 24 months.
QUESTIONS AND CONTACTS
For questions about the medicine, please consult your doctor or pharmacist. Manufacturer: FARMAPRIM SRL, 5 Crinilor str., Porumbeni village, Criuleni district, Republic of Moldova, MD-4829. Pharmacovigilance: safety@farmaprim.md.
Brief information prepared on the basis of the approved Summary of Product Characteristics. It does not replace consultation with a doctor or pharmacist and does not contain all information about the medicine. Always read the package leaflet.